Fig. 5
In vivo experiment result, CS: chitosan. (A). Representative micro-computed tomography (CT) images of the distal femurs at 4 w posttreatment. (B). Analysis of the distal femoral trabecular bone parameters using micro-CT. The micro-CT images of trabecular bone femurs after 4 w with comparative analyses of bone structural parameters, including bone volume/total volume (BV/TV), bone mineral density (in g/mm3, trabecular thickness (Tb. Th, in mm), and number of bone trabeculae (TB. N, in 1/mm). (C). Hemoxylin & eosin staining of femoral sections of mice at 4 w posttreatment. (D). Mankin’s criteria (femurs = 8 for each group). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001