Table 1 Design matrix of experiments proposed by response surface methodology (RSM) and the experimental units acquired for each experiment
| Â | Independent variables | Activity (U/ml) | |||
|---|---|---|---|---|---|
Run | A: Incubation time (min) | B: Taurine concentration (mmol/L) | C: Temperature (deg C) | Experimental | Predicted |
1 | 25 | 250 | 28 | 1.490 | 1.490 |
2 | 25 | 250 | 16 | 1.780 | 1.780 |
3 | 25 | 450 | 28 | 2.050 | 2.050 |
4 | 15 | 350 | 22 | 1.997 | 2.000 |
5 | 35 | 150 | 34 | 1.447 | 1.450 |
6 | 15 | 150 | 22 | 1.770 | 1.770 |
7 | 25 | 250 | 40 | 1.200 | 1.200 |
8 | 25 | 250 | 28 | 1.490 | 1.490 |
9 | 35 | 350 | 34 | 1.770 | 1.770 |
10 | 25 | 50 | 28 | 1.500 | 1.500 |
11 | 15 | 350 | 34 | 1.800 | 1.800 |
12 | 25 | 250 | 28 | 1.490 | 1.490 |
13 | 5 | 250 | 28 | 1.698 | 1.700 |
14 | 35 | 350 | 22 | 1.450 | 1.450 |
15 | 25 | 250 | 28 | 1.490 | 1.490 |
16 | 35 | 150 | 22 | 1.830 | 1.830 |
17 | 45 | 250 | 28 | 1.728 | 1.730 |
18 | 15 | 150 | 34 | 0.870 | 0.870 |