Fig. 6
From: Non-viral gene delivery to human mesenchymal stem cells: a practical guide towards cell engineering
Most used therapeutic genes and markers to induce and evaluate osteochondral differentiation. Abbreviations: BMP-2, -6, -7, -9: bone morphogenic protein 2, 6, 7, 9; siRNA: small interfering RNA; miRNA: micro-RNA; TGF-β1 and -β3: transforming growth factor-β1 and -β3; SOX9: sex-determining region Y-type high mobility group box 9; RUNX2: core binding factor alpha 2; OSX: osterix; ALP: alkaline phosphatase; COL-I, -II, -X: type-I, -II, and -X: collagen; OCN: osteocalcin; ACAN: aggrecan