Fig. 6From: Exosome-mediated crosstalk between epithelial cells amplifies the cell injury cascade in CaOx stone formationEffects of exosomes derived from HK2 cells under different conditions on oxidative stress injury and the MAPK signalling pathway in rat renal tissues with different treatments. A Measurement of CAT activity in the SD rats with different treatments. B MDA expression in the SD rats under different conditions. C SOD activity of the SD rats with different treatments. D ROS levels in the SD rats under different conditions. The expression of P-P38 was increased in the rats injected with EXO(S) or injected with GAM, pre-EXO(C) renal subcapsular injection could ameliorate these effects while pre-EXO(S) renal subcapsular injection could accelerate the expression of P-P38. There were no significant changes in the expression of P-JNK and P-ERK. The data are expressed as the mean ± SE. ∗P < 0.05Back to article page