Fig. 1
From: Engineering pH responsive fibronectin domains for biomedical applications
Schematic of cell surface endocytosis and recycling for EGFR and Fn3. Red arrows indicate trafficking of Fn3-EGFR complexes in endosomes (orange circles) to lysosomes for degradation. Black arrows denote movement of transport vesicles (yellow circles) carrying dissociated Fn3 and EGFR molecules to the cell exterior. White indentations denote sites of Fn3-EGFR complex internalization, i.e., sites of endosome formation